Büchel Lab

University Medical Center Hamburg-Eppendorf

Hamburg (DE6) · Germany

ERC-funded
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Research focus

ERC Advanced Grant · 2019

Psychobiological mechanisms of pain persistence

Persistent or chronic pain is a key medical and societal problem. In the last decades, biomedical research has undertaken enormous efforts to develop treatments for persistent pain, but the results have been disappointing. This project proposes a radical shift, namely to target the early development of pain persistence and to investigate psychological interventions directed at negative expectations, control and reward in experimental long-term pain studies. A methodological work package will develop novel tools, such as MR spectroscopy of the spinal cord, to track metabolic changes related to persistent pain, and to identify the mechanisms of the proposed interventions. All studies are…

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