Aarts Lab

Radboud University Nijmegen

Oost-Nederland (NL2) · Netherlands

ERC-funded
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ERC Starting Grant · 2019

The obesity spiral: inflammation and effortless fast food choices

Obesity is a major threat to human health, often characterized by increased consumption of energy-dense and easy-to-eat, ‘effortless fast food’. A better understanding of effort-related motivation in obesity is important to explain why healthy lifestyle changes are often so hard to maintain. Previously, I have demonstrated the neurocognitive and neurochemical processes underlying motivational control of behaviour. However, in obesity, findings about the motivation to overcome effort costs for food reward – and associated dopamine signalling - are inconsistent, suggesting another – yet unknown - variable. Here, I am the first to suggest that this variable is chronic low-grade inflammation -…

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