ERC Starting Grant · 2020
Reinforcement learning from post-ingestive calories: from body to brain in health and disease
The drive to eat is one of the strongest in the modulation of behaviour. Selection of food is guided by sensory feedback, including post-ingestive information about energy content, that has been studied across several species, paradigms and nutrients. In rodents, post-oral administration of sugar is associated with striatal dopamine release and conditions robust preferences, in part as a result of viscerosensory information transmitted through the vagus nerve. Consistently, in humans there is evidence that pairing a flavour with a tasteless carbohydrate will enhance pleasantness of the pre-ingestive stimulus and increase its consumption. However, available data in humans have provided…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.