ERC Starting Grant · 2024
A road to remember: Neural plasticity through the lens of gut-brain interactions
The fact that the brain is influenced by the microorganisms that make up the gut microbiome substantially widens the scope of how we need to view human neurocognition and behaviour. However, a clear understanding of underlying mechanisms is scant and mainly grounded in animal work. This proposal aims at major contributions towards overcoming these limitations. The core hypothesis is that gut bacteria are key in shaping neural plasticity, and in this way, influence human memory abilities. Changes in gut microbial signalling may contribute to altered neurocognition in individuals who are genetically predisposed to Alzheimer’s disease. MemoryLane’s results will thus also have important…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.