Vassena Lab

Radboud University Nijmegen

Oost-Nederland (NL2) · Netherlands

ERC-funded
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ERC Starting Grant · 2024

Cease or Persist: A multivariate mechanistic account of effortful persistence

Is this worth my effort? Should I persist and push through or give up and move on? We are constantly confronted with this fundamental question. Persisting through effortful endeavors at all costs is often the key to success in modern society. Reduced or excessive persistence is a hallmark dysfunction in many neuropsychiatric disorders (anxiety, depression, OCD, apathy, etc.) with massive individual and societal cost. Despite the urgency to better understand this process, how exactly we decide to cease or persist, and which cognitive, neural and neurochemical systems support persistence, remains unclear. With COPE, I propose a novel neuro-computational theory of effortful persistence, able…

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