Marques Lab

University of Minho

Continente (PT1) · Portugal

ERC-funded
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ERC Consolidator Grant · 2016

Cells-self Extracellular Matrices-based Bioinks to create accurate 3D diseased skin tissue models

It has been recognized that growing cells within 3D structures reduces the gap between 2D in vitro cell cultures and native tissue physiology. This has been paving the way for the development of reliable 3D in vitro cell-based platforms with major impact in the reduction/elimination of animal experimentation, diseases modelling and drug development. So far, the many strategies that have been followed to bioengineer in vitro 3D human tissue models mostly rely on the random culture of cells within a 3D structure without reflecting the compositional and structural complexity of the native tissues. Recently proposed bioprinting technologies that allow accurate and high speed deposition of…

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