ERC Consolidator Grant · 2018
Flow and Deformation of Cancer tumours near Yielding
The aim of this proposal is to understand when, how and why metastatic tumour cells detach from a tumour. Often, primary tumours do not kill patients, but secondary tumours do. These so-called metastatic tumour cells disassociate from a primary tumour and, ultimately, prove fatal. Currently, we do not understand the fundamentals of the biophysical pathways and mechanisms of the metastasis of cancer, hampering medical intervention. I propose a multidisciplinary approach, combining engineering, chemistry, biophysics and cell biology to identify the mechanical pathways for the creation of metastatic cancer cells. Biological cells in tissue are very densely packed, which locks them in place…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.