ERC Advanced Grant · 2020
Adolescent idiopathic scoliosis (AIS) is a 3D deformity of the spine affecting previously healthy children, substantially reducing their quality of life and creating a life-long burden of disease. Although it has been indentified since the time of Hippocrates (400 BC), we have not been able to rationally develop effective treatments and provide a cure for these children suffering from AIS because its cause and mechanism of disease are still unknown. ScoliStorm will create a paradigm shift in AIS research by uncovering its complex perfect storm of anatomical, biomechanical and mechanobiological causes in the intervertebral disc and exploring this disease mechanism whereby predictive triggers…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.