Noailly Lab

Pompeu Fabra University

Este (ES5) · Spain

ERC-funded
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ERC Consolidator Grant · 2021

Scalable systems modelling to simulate body-level interplays among non-communicable diseases

Non-communicable diseases (NCD) that involve load-bearing organs emerge silently according to complex mechanisms that are likely to involve inter-disease systemic communications. Clinical explorations cannot apprehend such intricate emergence, but I postulate that multiscale in silico models can. The digital twin for health has progressed a lot in the last decades, but multi-disease transversal modelling has not happened. It requires unique developments to couple small to large-scale model components with appropriate balance of phenomenological and mechanistic approaches, to cope with overwhelming biological complexity, preserve interpretability and incorporate real-world data. This is the…

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