ERC Starting Grant · 2021
Cancer is a global health burden. In-vitro pre-clinical models play a key role in fighting this burden by encompassing all the activities prior to clinical trials, from tumor microenvironment reconstruction to drug candidate selection. However, the frequent failure of promising pre-clinical drug candidates highlights two major drawbacks of these models: (i) the difficult reproduction of the dynamic cancer structure related to numerous physical cues; (ii) their experimental nature that suffers from high costs, long times, and limited understanding. Consequently, the relationship between dynamic physical cues, cell behavior, and drug efficacy is still unknown. CoDe4Bio tackles such a huge…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.