Viola Lab

Gran Sasso Science Institute (GSSI)

Sud (ITF) · Italy

ERC-funded
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Research focus

ERC Starting Grant · 2021

Using CARDIac simulations to run in-silicO clinical TRIALS

Clinical trials are a key tool for advancing medical knowledge, but they consist of a long and costly process entailing the recruitment of a representative cohort of participants to properly account for the population statistical variability. Computational engineering is a promising approach to gain more insight into patients' cardiac pathologies and to test innovative medical devices before running conclusive in-vivo experiments on animals or medical trials on humans. This technological breakthrough, however, is limited by some technical and epistemic challenges: (i) the reliability of cardiovascular computational models depends on the accurate solution of the hemodynamics coupled with the…

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