ERC Starting Grant · 2023
Personalised Mechanobiological Models to Predict Tumour Growth and Anti-Cancer Drug Penetration
Personalised cancer medicine presents an exciting frontier in healthcare that tailors disease mitigation and intervention to an individual patient. However, existing technologies fail to leverage the physical forces that underpin stress-dependent tumour growth and the subsequent evolution of biomechanical resistance to anti-cancer drugs. Furthermore, the fundamental mechanisms governing such force-sensitivity have yet to be uncovered; this deficiency in scientific understanding of the active biomechanical behaviour of tumours and control of drug penetration has hindered the progression of anti-cancer therapy. In this project, an advanced computational modelling framework will first be…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.