Moroni Lab

Maastricht University

Zuid-Nederland (NL4) · Netherlands

ERC-funded
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ERC Advanced Grant · 2024

Directing Stem Cell Activity through Mechanical Stimulation of Metamaterial 3D Scaffolds

Regenerative medicine aims at repairing damaged tissues in our body. To do so, stem cells are often used. My research has been focused on biofabrication innovations for tissue engineering, which aims to direct stem cell fate to steer tissue regeneration. While mechanical loading play a determinant role in the organization of adult cells and tissue development, and my past work with 3D scaffolds demonstrated the importance of mechanical cues to direct stem cell fate, very little is known about its influence on pluripotent stem cells (PSCs). PSCs are a powerful resource for tissue engineering whose application currently suffers from many limitations. One such limitation is the reliance on…

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