Mota Lab

Maastricht University

Zuid-Nederland (NL4) · Netherlands

ERC-funded
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Research focus

ERC Consolidator Grant · 2024

Nurturing Environment - BioPrinting Human Renal Organ Networks

Chronic kidney disease (CKD) results in loss of kidney function in patients, ultimately requiring organ transplant. Critical organ shortage and organ rejection after transplant make extended dialysis inevitable and the only therapy available. To exacerbate this problem, the incidence of CKD is increasing worldwide, with >14% of the general population affected. Hence, there is an urgent need for novel therapies. Induced pluripotent stem cells have been used to create kidney organoids representing early renal development stages. These organoids might be a suitable therapy in the future but fundamental challenges to achieve late stages of physiologically relevant maturation and function need…

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