Macmanus Lab

National University of Ireland - University College Dublin

Ireland (IE0) · Ireland

ERC-funded
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ERC Starting Grant · 2024

Bridging the sex gap in traumatic brain injury biomechanics

Traumatic brain injury (TBI) is a multi-anatomical-scale mechanical injury affecting 30 million women globally each year. brainsex will focus on the sex specific biomechanics of TBI in the elderly population motivated by the highest reported incidence of TBI in people over 75 years old. Furthermore, in the elderly population women account for more TBIs than men. However, women remain underrepresented in TBI research. Finite element brain models (FEBMs) have played a major role in improving our understanding of TBI. However, current FEBMs have been developed using male-only data and cannot accurately model female TBI due to the distinct sex specific neuroanatomies. I will embark on frontier…

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