ERC Consolidator Grant · 2025
Cancer-Osteocyte NeTwoRk Atlas
Metastatic breast cancer claims the lives of more European women than any other cancer, and is an ever-growing problem in an aging global population that increasingly survives treatment of primary cancer. The most common site for metastatic breast lesions is bone, with 75% of patients experiencing pathological fractures, spinal cord compression or severe bone pain. Crosstalk between cancer cells and osteocytes, which make up more than 90% of our bone cells and form a complex sensing and signalling network throughout our bones, has recently been implicated in this process. As we now know that breast cancer cells are already present in the bone marrow by the time a primary tumour has been…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.