Kruk Lab

Delft University of Technology

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Starting Grant · 2025

Diversity Outside In: A new era in musculoskeletal modelling by integrating in-vivo parameters to reflect human heterogeneity.

Musculoskeletal disorders, affecting muscles, bones, joints, and associated tissues, are the leading cause of disability worldwide today. To guide professionals in preventing and treating musculoskeletal disorders, musculoskeletal models serve as powerful tools. Given that these disorders present differently between sexes and throughout the lifespan, it is crucial to include model parameters that reflect this diversity. However, while it is widely recognized in medicine and science that women and men are not simply scaled versions of one another, the field of biomechanics still relies on linear scaling of musculoskeletal models based on male bone geometry and mixed-sex muscle parameters.…

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