Khammash Lab

Research focus

ERC Advanced Grant · 2016

Cybergenetics: Theory and Design Tools for Biomolecular Control Systems

We propose to develop a new theory and design tools for the estimation and real-time control of living cells. The control systems designed using these tools will precisely and robustly steer the dynamic behavior of living cells in real time to achieve desired objectives. Cells would be controlled either collectively at the population level, or individually as single cells. The control systems achieving this regulation will be realized either on a digital computer that is interfaced with living cells, or using de novo genetic circuits that are introduced into the cells where they are designed to function as molecular control systems. Our methods will explicitly confront the numerous…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.