ERC Starting Grant · 2018
Label-free optical nanoscopy, free from photobleaching and photochemical toxicity of fluorescence labels and yielding 3D morphological resolution of <50 nm, is the future of live cell imaging. 3D-nanoMorph breaks the diffraction barrier and shifts the paradigm in label-free nanoscopy, providing isotropic 3D resolution of <50 nm. To achieve this, 3D-nanoMorph performs non-linear inverse scattering for the first time in nanoscopy and decodes the information of multiple scattering between sub-cellular structures (organelles). 3D-nanoMorph innovatively devises complementary roles of light measurement system and computational nanoscopy algorithm. A novel imaging system serves the specific…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.