Baraban Lab

Helmholtz Centre Dresden-Rossendorf

Sachsen (DED) · Germany

ERC-funded
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Research focus

ERC Consolidator Grant · 2021

Nano-assisted digitalizing of cancer phenotyping for immunotherapy

Every day cancer takes about 30000 lives worldwide, despite multiple treatments developed in the last 50 years. True revolution in the therapy is demonstrated by the immunooncology relying on multiple routes to activate the immune system, using e.g. Chimeric Antigen Receptors, checkpoints inhibitors. Although demonstrating success in the treatment of e.g. lymphoma, the percentage of patients responding to the immunotherapy is less than 30%. Even more, the activation of immune system does not happen at no cost, leading to severe auto-immune reactions, sometimes with lethal consequences. Therefore, the main question of clinicians is: how to efficiently predict the response/no-response of the…

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