Caneva Lab

Delft University of Technology

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Starting Grant · 2021

Single-Molecule Acousto-Photonic Nanofluidics

Reading biomolecular signatures and understanding their role in health and disease is one of the greatest scientific challenges in genome and proteome biology. Yet, complete protein analysis at the single-molecule level remains an unmet milestone. This pursuit is fundamentally hindered by the huge dynamic range of protein cell expression and the insufficient spatio-temporal resolution of current analysis methods. Next-generation single-molecule techniques that can precisely manipulate and sequence proteins in space and time are urgently needed to reach this goal. Among these, nanopore platforms are at the forefront, leading in terms of read length, throughput and sensitivity. However, the…

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