Boer Lab

Free University and Medical Center Amsterdam (VU-VUmc)

West-Nederland (NL3) · Netherlands

ERC-funded
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Research focus

ERC Advanced Grant · 2023

In vivo Immunofluorescence-Optical Coherence Tomography

Current clinical medicine relies on MRI and CT for structural imaging, and immuno-PET/SPECT for molecular specificity. The combination of structural imaging and molecular specific imaging provides detailed information about expression of proteins and cell surface receptors in vivo in humans. PET-CT/MRI has become an essential component of personalized medicine. However, the resolution of MRI/CT is just under a millimeter, while the resolution of PET is limited to about 2-10 millimeters, insufficient for early disease detection. Moreover, PET is associated with radiation burden of ligands labeled with a radiotracer and can image only one labeled ligand at a time. What is missing is the…

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