Raspopovic Lab

University of Medicine Vienna

Ostösterreich (AT1) · Austria

ERC-funded
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ERC Consolidator Grant · 2023

Revolutionizing diabetes management by combining in silico models and AI control for vagus neuroprostheses

Diabetes is a major world health problem, approaching epidemic proportions and causing long term health damages due to inappropriate blood glucose regulation. Pharmacological therapies are limited by numerous side effects (as renal insufficiency or heart failure) and dose management issues. Their efficacy is also hindered by often problematic, patients’ compliance. This results in an unmet need for automatized, closed-loop glucose metabolism regulation, adaptable to variable patients’ conditions. Vagus nerve (VN) is a major component of the autonomous nervous system innervating internal organs, and its electrical stimulation showed preliminary results in modulating glucose metabolism.…

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