Calatroni Lab

University of Genoa

Nord-Ovest (ITC) · Italy

ERC-funded
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ERC Starting Grant · 2023

Model-aware learning for imaging inverse problems in fluorescence microscopy

This project will develop model-aware, i.e. physics-informed, learning methods for solving imaging inverse problems (IIPs) in fluorescence microscopy imaging (FMI). IIPs are frequently encountered in FMI whenever a visual representation of a biological sample needs to be reconstructed from incomplete and noisy input measurements. Such IIPs are typically ill-posed: their solution (if it exists) is unstable to perturbations. Classical model-based approaches reformulate the IIP at hand as an energy minimisation task. Such approaches rely both on the (approximate) knowledge of the complex physical processes involved and on the mathematical design of hand-crafted optimisation methods whose…

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