Chaigne Lab

Research focus

ERC Starting Grant · 2023

All-optical photoacoustic imaging for neurobiology

easuring the electrical activity of neurons in vivo is of paramount importance to understand the underlying principles of the brain. Current imaging techniques fail to capture this activity across the entire brain with sufficient spatial or temporal resolutions, while leaving brain tissue intact. Non-linear fluorescence microscopy, the most widespread optical imaging modality in system neurobiology, provides optical diffraction limited resolution and high frame rate, but is limited to shallow depth due to light scattering in tissue. Single-neuron activity in brain regions deeper than one millimeter can therefore not be probed. Combining widefield optical excitation and ultrasonic detection,…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.