Accanto Lab

Institute for Bioengineering of Catalonia

Este (ES5) · Spain

ERC-funded
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ERC Starting Grant · 2023

A two-photon compound fiberscope to study the brain at all spatial and temporal scales.

Understanding how neuronal circuits process information is a major scientific challenge, which demands new tools to address the complexity of the brain in animals during natural functioning. Two-photon (2P) microscopy, combined with optogenetics, has revolutionized neuroscience thanks to the possibility to image and photostimulate neuronal activity with light, but suffers from important limitations. To determine how perception and behaviour arise, we need to record and manipulate at will the activity of every neuron in a circuit in freely behaving animals. 2P microscopy is on the contrary mainly performed in head-fixed animals, which poses a clear limitation to the study of natural…

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