Edelmann Lab

Technical University of Munich

Bayern (DE2) · Germany

ERC-funded
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ERC Starting Grant · 2024

Nanorobotic microgels to control stem cell fate

Myocardial infarction continues to claim the lives of millions of people every year, and survivors are often left with severe health issues. Transplanting cardiac cells engineered from human stem cells into the injured heart is a particularly promising approach to repairing damaged cardiac tissue. Despite extensive research on stem cell-based therapies, a major limitation is effectively regulating stem cell differentiation. Mechanically training stem cells throughout culture could be solution, by exploiting their mechanosensitive nature. However, there is currently a lack of technology that can recreate the mechanically dynamic microenvironment of tissue. Therefore, I aim to develop an…

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