Slenders Lab

Italian Institute of Technology

Nord-Ovest (ITC) · Italy

ERC-funded
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ERC Starting Grant · 2025

Comprehensive Platform for Correlating Biomolecular Dynamics and Biomechanics with Multiscale Optical Spectroscopy

Measuring the molecular dynamics and interactions of biomolecules in live cells is crucial for understanding cellular mechanisms. While recent advances in super-resolution fluorescence microscopy have enabled molecular-level resolution in fixed samples, capturing dynamics in live cells remains a major challenge. Conventional methods for studying molecular dynamics struggle with high fluorophore concentrations, photobleaching, and the need for extensive prior knowledge about the setup and sample. In addition, measuring the molecular diffusion properties without knowing the local viscosity complicates the study of anomalous diffusion dynamics. The overall goal of the MotionPicture project is…

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