Titz Lab

Helmholtz Centre for Infection Research

Niedersachsen (DE9) · Germany

ERC-funded
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Research focus

ERC Starting Grant · 2016

Sweet Theranostics in Bitter Infections - Seek and Destroy

Bacterial infections are now a global threat demanding novel treatments due to the appearance of resistances against antibiotics at a high pace. The ESKAPE pathogens are those with highest importance in the EU and chronic infections due to biofilm formation are a particular task. Noninvasive pathogen-specific imaging of the infected tissue is not clinically available. Its successful implementation will enable the choice of appropriate therapy and boost efficacy. Furthermore, Gram-negative bacteria have a highly protective cellular envelope as an important resistance mechanism for drugs acting intracellularly, resulting in an alarmingly empty drug-pipeline. To overcome this gap, I will…

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