Patureau Lab

Technical University of Aachen

Nordrhein-Westfalen (DEA) · Germany

ERC-funded
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ERC Starting Grant · 2016

Development of Direct Dehydrogenative Couplings mediated by Dioxygen

The field of C-H bond activation has evolved at an exponential pace in the last 15 years. What appeals most in those novel synthetic techniques is clear: they bypass the pre-activation steps usually required in traditional cross-coupling chemistry by directly metalating C-H bonds. Many C-H bond functionalizations today however, rely on poorly atom and step efficient oxidants, leading to significant and costly chemical waste, thereby seriously undermining the overall sustainability of those methods. As restrictions in sustainability regulations will further increase, and the cost of certain chemical commodities will rise, atom efficiency in organic synthesis remains a top priority for…

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