Jiménez-Barbero Lab

Biosciences Cooperative Research Center (CIC bioGUNE)

Noreste (ES2) · Spain

ERC-funded
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ERC Advanced Grant · 2017

Breaking the limits in glycan recognition by NMR

Carbohydrates (glycans, sugars) play key roles in virtually all biological events. Given their chemical complexity, understanding their roles in nature requires a multidisciplinary approach. Research in the field is growing, since advances in the area could be part of the solution to many health issues. However, we lack full knowledge on the role of most glycan-mediated events especially at the resolution required from a chemical perspective to manipulate them and create new probes and eventually drugs. Understanding sugar recognition remains a major challenge in science. Although X-ray diffraction has been employed to study sugar/protein complexes, a recent report has highlighted that most…

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