ERC Consolidator Grant · 2017
Dynamic Activatable Fluorophores
In DYNAFLUORS I will develop the first chemical toolbox for imaging in real time the activity of immune cells in tumours. Although the management of cancer has improved over the years, the cure rates for patients with metastasis and advanced tumours remain low due to lack of appropriate therapies. Recent studies suggest that drugs empowering host immune cells (i.e. immunotherapies) are promising approaches for intractable tumours. However, there are no tools to visualise and understand how host immune cells stop cancer progression in vivo. This important unmet challenge drives the ambitious targets of this proposal. Over the past 10 years, I have pioneered the development of chemical…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.