ERC Advanced Grant · 2018
Hydrogen Bonding Phase Transfer Catalysis
The objective of the research described in this proposal is to develop a new mode of activation for catalysis leading to more sustainable catalytic processes using abundant feedstock materials. By merging hydrogen bonding and phase transfer catalysis, we propose that hydrogen bonding of an insoluble unreactive anionic nucleophile with a hydrogen bond donor catalyst will form a soluble and reactive entity now capable of carbon-nucleophile bond formation with concomitant release of the hydrogen bond donor catalyst. This activation mode is applicable to nucleophiles as simple as feedstock inorganic salts enabling challenging asymmetric bond-forming reactions in a general and predictable…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.