Besenius Lab

University of Mainz

Rheinland-Pfalz (DEB) · Germany

ERC-funded
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Research focus

ERC Consolidator Grant · 2018

Supramolecular engineering of glycan-decorated peptides as synthetic vaccines

The main and most important feature of vaccines is the induction of an immunological memory response, which is key to providing long-term protection against pathogens. The current strategies for potent antibacterial and antiviral vaccines employ conjugation of pathogen specific entities onto carrier proteins, and are limited to formulations that suffer from low stability and short shelf-lives, and are thus not viable in developing countries. Strategies for the development of new vaccinations against endogenous diseases like cancer further remain an unmet challenge, since current methodologies suffer from a lack of a modular and tailored vaccine-specific functionalisation. I therefore…

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