ULB - Free University of Brussels
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest (BE1) · Belgium
ERC Starting Grant · 2018
Transport of phosphorylated compounds across lipid bilayers by supramolecular receptors
This ORGANITRA project addresses transmembrane transport. Lipid bilayer membranes not only define the borders of cells and their compartments but are also implicated in metabolic processes and signal transduction. Membranes function as impermeable barriers for ionic and hydrophilic species which can only cross the membrane with the aid of dedicated membrane proteins. For biotechnological and biophysical applications, the development of anion carriers that can bind an anion and transport it across the lipid bilayer could be of great relevance. In this project, synthetic anion receptors will be developed to bind biologically relevant organic phosphorylated compounds, like nucleotides. These…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.