Wezenberg Lab

Leiden University

West-Nederland (NL3) · Netherlands

ERC-funded
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Research focus

ERC Starting Grant · 2018

From light-stimulated anion receptors to transmembrane carriers and pumps

The transport of anions across the cell membrane, which is mediated by transport proteins, is essential to many important biological processes. Dysregulation of this transport has been associated to various diseases and therefore, chemists endeavour to develop artificial receptors that mimic the function of natural transporters. Despite much progress over the last decade, the current artificial systems are mostly static, while proteins are able to change their activity dynamically in response to stimuli in the environment. To integrate such stimuli-controlled behavior in synthetic systems is a key contemporary challenge. In view of this, the goal of the proposed research program is to…

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