Bastings Lab

Swiss Federal Institute of Technology Lausanne (EPFL)

- · Switzerland

ERC-funded
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Research focus

ERC Starting Grant · 2020

Intracellular Action of DNA-based Nano-materials

Self-organization of matter into structured architectures with emerging functionality is arguably the most important phenomenon to enable life. Unfortunately, human efforts to successfully engineer materials that control hierarchical order and achieve precise action in cells, have suffered from structural heterogeneity and limitations in functional precision. Immune pathways are prime examples of cascades where a finely balanced sequence of interactions decides between life-changing outcomes, varying from tolerance to active fight. Immune-modulating materials, therefore, would uniquely benefit from precision control over functionality. DNA-based nanomaterials have the potential to change…

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