Gemmeren Lab

University of Kiel

Schleswig-Holstein (DEF) · Germany

ERC-funded
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ERC Starting Grant · 2020

Dual Ligand-Enabled Palladium Catalysis: Unlocking Novel Reactivities and Selectivities in Aromatic C–H Activation

The transition metal catalyzed activation of aromatic carbon-hydrogen (C–H) bonds has enabled a variety of novel transformations that complement traditional approaches towards complex aromatic compounds. The vast majority of methods developed in this field relies on the use of directing groups, which coordinate the catalyst prior to the C–H activation step to induce activity and selectivity. In contrast, nondirected methods have remained underdeveloped, since it has remained highly challenging to achieve reactivity and induce good selectivities in such processes. My research group has recently discovered a new design paradigm for palladium catalysts, which exhibit extraordinary activities…

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