ERC Starting Grant · 2021
Chemical Tools for Transcriptome-wide Analysis and Modulation of RNA
RNA is an essential biomolecular polymer that exhibits many cellular functions ranging from catalytic to informational that are crucial for life. Long considered as DNA's unexciting counterpart, RNA has in recent years transcended its dull image, driven by pivotal discoveries of its involvement in cellular signalling pathways. Despite the clear importance of RNA in biology and medicine, many of its properties and functions remain elusive. In the RiboChem program we will develop ground-breaking chemical tools for uncovering the identity, function, structure and druggability of RNA on an unparalleled transcriptome-wide level, with a special focus on riboswitches. Riboswitches are structured…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.