ERC Consolidator Grant · 2022
Multifaceted molecular MRI toolbox to uncover Zn2+ in physiology and pathology
To reveal the multiple aspects (molecular, cellular and anatomical) of a studied biological process (in health or disease), it is necessary to have the ability to spatially map the multiplexity and dynamicity of intra- and inter-cellular events in the context of a whole organism. We here propose a conceptually novel approach to spatially map the multicomponent information of a studied biological phenomenon, from the deep tissue of a studied subject using a single imaging setup. In realizing the importance and diverse roles of labile Zn2+ in specific tissues, we aim to develop ZincMRI. ZincMRI is a molecular imaging toolbox designed to provide orthogonal MRI readouts, with which we aim to…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.