Guérard Lab

Research focus

ERC Consolidator Grant · 2022

Stable 211At-labeled radiopharmaceuticals for targeted α therapy

Astatine (At) is the rarest naturally occurring Astatine (At) is the rarest naturally occurring element on Earth, exhibiting only short-lived radioisotopes. One of them, 211At, decays with a half-life of 7.2 h by emission of a highly energetic alpha particle, making it one of the rare alpha emitters suitable for targeted alpha therapy (TAT) of cancers, if bound to an appropriate cancer targeting molecule. Because the number of cyclotrons able to produce it has seen a significant rise in the past years, it is expected that 211At will become more accessible and play a major role in the development of TAT. Astatine belongs to the halogen elements, and despite more than 80 years since its…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.