ERC Starting Grant · 2022
The Single-Centre Ambiphile ligand Concept: Cooperative Systems for Waste-free Catalysis
The addition of ammonia to alkenes, which could produce amines in a 100% atom efficient process, has never been achieved by a molecular catalytic system and stands as a modern Holy Grail for the synthetic chemist. Alkyl amines, a major chemical commodity, are typically accessed through stoichiometric methods, even employing toxic N1 feedstocks such as hydrogen cyanide. The fundamental barrier to utilizing ammonia as an N1 feedstock lies in its activation, with a high N-H bond energy and a preference for acting as a neutral donor ligand in organometallic systems. In order to employ ammonia in catalytic transformations, new bond-activation concepts which address these fundamental pitfalls are…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.