ERC Starting Grant · 2022
Reconstructing enzymes for novel nitrogen-nitrogen bond forming chemistry
Nitrogen-nitrogen (N-N) bonds have fascinating structural and functional properties, are ubiquitously found in diverse pharmaceuticals and fine chemicals, and represent important key structural motifs in diverse natural products, endowing them with potent biological activities. However, traditional chemical procedures to synthesize N-N bond-containing compounds are often difficult to realize, costly and environmentally unfriendly. In addition, the formation of intermolecular N-N linkages is particularly difficult and remains a mostly unaddressed problem in chemistry. ReCNNSTRCT will address this challenge by decoding novel reaction chemistries from the underexploited family of N-N…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.