ERC Starting Grant · 2022
Glycan foldamers: designing oligosaccharides to build three-dimensional architectures
Natural biopolymers have inspired the development of synthetic analogues – i.e. foldamers – capable of adopting defined conformations and forming programmable three-dimensional architectures. These compounds are mainly based on peptides and nucleic acids, that are well understood at the molecular level. The diversity, intrinsic chirality, and ability to generate hierarchical assemblies suggest that carbohydrates hold an even larger potential for the generation of three-dimensional structures. However, the complexity of carbohydrate synthesis and structural analysis have prevented access to synthetic carbohydrates capable of adopting defined geometries. I propose the creation of carbohydrate…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.