Pappas Lab

University of Freiburg

- · Germany

ERC-funded
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ERC Starting Grant · 2023

Developing Roles for Phosphates Outside of Biology: A Systems Chemistry Approach Towards Abiotic Phosphate Fuels

Phosphates and phosphate esters underpin biological information transfer, signal transduction, and contribute to the energetics of life. Biochemical fuels that include phosphates (ATP, GTP) drive selective processes, by incorporating chemical information (A vs. G) in their fuel structure. Despite the multifaceted role of phosphates in biology, their use in supramolecular systems chemistry remains largely underexplored. PhosphotoSupraChem develops roles for phosphates outside of biology and capitalizes on the idea of providing chemical information within abiotic phosphate fuels to control selectivity and reactivity in the context of fuel-driven structure formation. The information is…

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