ERC Advanced Grant · 2024
Harnessing Non-Classical Carbocations for Stereoselective Synthesis
Stereoselective synthesis is a central aspect of modern organic chemistry, enabling the precise formation of specific stereoisomers in complex molecular architectures. Key to this process are reactive intermediates such as carbenes, radicals, and carbocations. However, achieving complete stereocontrol over non-classical carbocations in the stereoselective synthesis of acyclic molecules remains a formidable challenge. These fascinating carbocations, despite decades of research, exhibit unpredictable reactivity, making the controlled creation of stereocenters particularly difficult. In this proposal, our primary goal is to achieve comprehensive stereocontrol over non-classical carbocations.…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.