ERC Starting Grant · 2024
Molecular Editing by Nitrogen Insertion
NINSERT constitutes a program to embark on selective and mild nitrogen insertions, both within and beyond carbonyl chemistry. Reagent development, catalyst design, and synergistic effects will be evaluated to provide a platform for late-stage skeletal editing, an area that has been recently brought to the forefront of organic chemistry. With a primary emphasis on heterocyclic motifs, commonly encountered in natural products and drug candidates, NINSERT offers a powerful tool to streamline future syntheses of nitrogen containing compounds. Notably, approximately 59% of all small-molecule drugs feature nitrogen heterocycles, underscoring the profound impact this program will have on…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.