Gnaim Lab

Weizmann Institute

- · Israel

ERC-funded
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ERC Starting Grant · 2024

Electrochemical Borylation via Borylene Species: Bridging a Gap in Synthetic Chemistry

Carbenoids (carbene and nitrene) have revolutionized the field of organic chemistry, reshaping and improving the molecular construction landscape and unveiling previously inaccessible reaction pathways. This chemistry has massively simplified the synthesis of complex molecular structures, such as pharmaceuticals, agrochemicals, and polymers. In contrast with the essential role of carbenes and nitrenes, the boron analogue - borylene - has received limited attention in synthetic chemistry. A basic understanding of borylene reactivity has hindered its utilization in organic synthesis, primarily because of its synthetically challenging formation. This proposal aims to harness electrochemistry…

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