ERC Consolidator Grant · 2016
Reverse Engineering Gene Regulatory Networks
Gene regulatory networks (GRNs) are an important cellular signal processing mechanism for translating input signals into appropriate phenotypes by modulating expression of the genome. The quantitative details of how cells process information through GRNs are still poorly understood, but of central importance in a large number of biological processes. Considerable progress has been made in mapping the topology of GRNs and more recently in deciphering the relationship between promoter sequence and function. Nonetheless, it is not yet possible to computationally predict the output of most native promoters, nor is it trivial to build promoters that integrate signals in a novel and predictive…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
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