Wilhelm Lab

National Centre for Scientific Research (CNRS)

Ile-de-France (FR1) · France

ERC-funded
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ERC Consolidator Grant · 2019

Bioinorganic intracellular synthesis of photo-responsive bio-camouflaged nanomedicines

Exposed to smart man-engineered nanomedicines, cells can profoundly transform and recycle them. To communicate, or in response to exogenous stress, cells generate extracellular vesicles which can play crucial roles in multiple physiological processes, as for instance, and unfortunately, for cancer progression. The goal of this proposal is to combine both biological events to deliver nanomedicines created by cells only, using mesenchymal stem cells as the most relevant cell model. The focus of this proposal on nano-bio-production is three-fold. - In the first instance, I aim to rationally develop novel strategies for bioinorganic intracellular synthesis of nanoparticles. The first aspect…

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